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・ Pierre Even (composer)
・ Pierre Even (producer)
・ Pierre Eyt
・ Pierre F. Brault
・ Pierre F. Côté
・ Pierre F. Goodrich
・ Pierre Faber
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・ Pierre Fabre (businessman)
・ Pierre Delorme
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Pierre Deniker
・ Pierre Denis
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Pierre Deniker : ウィキペディア英語版
Pierre Deniker
Pierre Deniker (1917, Paris - 1998〔http://www.fondationpierredeniker.net/〕) was involved, jointly with Jean Delay and J. M. Harl, in the introduction of chlorpromazine (Thorazine), the first antipsychotic used in the treatment of schizophrenia, in the 1950s.〔Kandel, E. R. (2007). ''In Search of Memory. The Emergence of a New Science of Mind.'' W. W. Norton & Co. See also (A review in Spanish about Kandel's book )〕 Thorazine had been used in surgical procedures peri-operatively as an anti-nausea medication in France. Patients were noted to be less anxious and calmer. This observation eventually led Deniker to try chlorpromazine with patients who had schizophrenia, where he observed notable improvement in symptoms.
The pharmaceutical company Smith-Kline had purchased the chlorpromazine rights from Rhone-Poulenc in France and had been marketing it as an anti-nausea medication. After Deniker's observations, they sought and received FDA approval in 1954 to market Thorazine for the treatment of schizophrenia.
==References==




抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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